GTPBP3 Antibody
CATALOG NUMBER: 60-598- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 52 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GTPBP3
- ADDITIONAL NAMES: tRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1, GTPBP3, MTGP1
- Protein Accession Number: Q969Y2
- PROTEIN GI NUMBER: 313104112
- NCBI GENE ID NUMBER: 84705
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This locus encodes a GTP-binding protein. The encodedprotein is localized to the mitochondria and may play a role inmitochondrial tRNA modification. Polymorphisms at this locus may beassociated with severity of aminoglycoside-induced deafness, adisease associated with a mutation in the 12S rRNA. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
- 1: Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
- 2: Villarroya, M., et al. Mol. Cell. Biol. 28(24):7514-7531(2008)
- 3: Bykhovskaya, Y., et al. Mol. Genet. Metab. 83(3):199-206(2004)
- 4: Li, X., et al. Biochem. Biophys. Res. Commun. 312(3):747-754(2003)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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