Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-334 amino acids from the C-terminal region of human GTF3A.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 42 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GTF3A
- ADDITIONAL NAMES: Transcription factor IIIA, TFIIIA, GTF3A
- Protein Accession Number: Q92664
- PROTEIN GI NUMBER: 172045838
- NCBI GENE ID NUMBER: 2971
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The product of this gene is a zinc finger protein withnine Cis[2]-His[2] zinc finger domains. It functions as an RNApolymerase III transcription factor to induce transcription of the5S rRNA genes. The protein binds to a 50 bp internal promoter inthe 5S genes called the internal control region (ICR), andnucleates formation of a stable preinitiation complex. This complexrecruits the TFIIIC and TFIIIB transcription factors and RNApolymerase III to form the complete transcription complex. Theprotein is thought to be translated using a non-AUG translationinitiation site in mammals based on sequence analysis, proteinhomology, and the size of the purified protein. [provided byRefSeq].
- 1: Wu, C., et al. Proteomics 7(11):1775-1785(2007)
- 2: Newton-Cheh, C., et al. BMC Med. Genet.SUPPL 1, S7 (2007) :
- 3: Weser, S., et al. Nucleic Acids Res. 31(9):2408-2416(2003)
- 4: Hanas, J.S., et al. Gene 282 (1-2), 43-52 (2002) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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