GTF2A1L Antibody
CATALOG NUMBER: 57-690- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This GTF2A1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human GTF2A1L.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 52 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GTF2A1L
- ADDITIONAL NAMES: TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
- Protein Accession Number: Q9UNN4
- PROTEIN GI NUMBER: 327478545
- NCBI GENE ID NUMBER: 11036
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The assembly and stability of the RNA polymerase IItranscription pre-initiation complex on a eukaryotic core promoterinvolve the effects of TFIIA on the interaction betweenTATA-binding protein (TBP) and DNA. This gene encodes a germcell-specific counterpart of the large (alpha/beta) subunit ofgeneral transcription factor TFIIA that is able to stabilize thebinding of TBP to DNA and may be uniquely important to testisbiology. Alternative splicing for this locus has been observed andtwo variants, encoding distinct isoforms, have been identified.Co-transcription of this gene and the neighboring upstream genegenerates a rare transcript (SALF), which encodes a fusion proteincomprised of sequence sharing identity with each individual geneproduct.
- 1: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 2: Kim, M., et al. J. Biol. Chem. 281(45):34288-34298(2006)
- 3: Howe, M.L., et al. Stem Cells Dev. 15(2):175-190(2006)
- 4: Huang, M., et al. Int. J. Mol. Med. 17(4):599-604(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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