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GSTP1 Antibody [3F2C2]GSTP1 Antibody [3F2C2]
GSTP1 Antibody [3F2C2]
GSTP1 Antibody [3F2C2]

GSTP1 Antibody [3F2C2]

CATALOG NUMBER: 32-167
  • Clonality: Monoclonal
  • Tested Applications: E, IHC, WB
  • Host Species: Mouse
  • Species Reactivity: Human
  • Conjugate: Unconjugated
  • Size: 0.1 mg

Specifications

  • HOST SPECIES: Mouse
  • SPECIES REACTIVITY: Human
  • IMMUNOGEN: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: E, IHC, WB
  • APPLICATION NOTE: Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    IHC(F):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

Properties

  • CLONALITY: Monoclonal
  • ISOTYPE: IgG1
  • BUFFER: Ascitic fluid containing 0.03% sodium azide.
  • CONCENTRATION: batch dependent
  • STORAGE CONDITIONS: GSTP1 monoclonal antibody can be stored at -20°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

  • NCBI OFFICIAL SYMBOL: GSTP1
  • ADDITIONAL NAMES: FAEES3, GST3, GST class-piPI, DFN7, GSTP, FAEES3, HEL-S-22
  • Protein Accession Number: P09211
  • PROTEIN GI NUMBER: 121746
  • NCBI GENE ID NUMBER: 2950
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background

  • GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
  • 1: Kimihiko Satoh, Ken Itoh, Masayuki Yamamoto. 2002. Carcinogenesis. 23: 457 - 462.
  • 2: Kimihiko Satoh, Ken Itoh, Masayuki Yamamoto. 2002. Carcinogenesis. 23: 457 - 462.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 32-167

  • Size: 0.1 mg
  • List Price: $365.00
Datasheet
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