Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 38 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GRAP2
- ADDITIONAL NAMES: GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
- Protein Accession Number: O75791
- NCBI GENE ID NUMBER: 9402
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the GRB2/Sem5/Drk family.This member is an adaptor-like protein involved inleukocyte-specific protein-tyrosine kinase signaling. Like itsrelated family member, GRB2-related adaptor protein (GRAP), thisprotein contains an SH2 domain flanked by two SH3 domains. Thisprotein interacts with other proteins, such as GRB2-associatedbinding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2),through its SH3 domains. Transcript variants utilizing alternativepolyA sites exist.
- 1: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 2: Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
- 3: Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- 4: Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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