GPER Antibody
CATALOG NUMBER: 58-136- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This GPER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human GPER.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 42 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GPER1
- ADDITIONAL NAMES: G-protein coupled estrogen receptor 1, Chemoattractant receptor-like 2, Flow-induced endothelial G-protein coupled receptor 1, FEG-1, G protein-coupled estrogen receptor 1, G-protein coupled receptor 30, GPCR-Br, IL8-related receptor DRY12, Lymphocyte-derived G-protein coupled receptor, LYGPR, Membrane estrogen receptor, mER, GPER1, CEPR, CMKRL2, DRY12, GPER, GPR30
- Protein Accession Number: Q99527
- PROTEIN GI NUMBER: 3023539
- NCBI GENE ID NUMBER: 2852
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is a member of the G-protein coupled receptor 1family and encodes a multi-pass membrane protein that localizes tothe endoplasmic reticulum. The protein binds estrogen, resulting inintracellular calcium mobilization and synthesis ofphosphatidylinositol 3,4,5-trisphosphate in the nucleus. Thisprotein therefore plays a role in the rapid nongenomic signalingevents widely observed following stimulation of cells and tissueswith estrogen. Alternate transcriptional splice variants whichencode the same protein have been characterized. [provided byRefSeq].
- 1: Patel, V.H., et al. Int. J. Mol. Med. 26(2):193-199(2010)
- 2: Ignatov, A., et al. Breast Cancer Res. Treat. 123(1):87-96(2010)
- 3: Li, Y., et al. Mol. Endocrinol. 24(5):969-980(2010)
- 4: Kang, L., et al. Mol. Endocrinol. 24(4):709-721(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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