Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GPAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-73 amino acids from the N-terminal region of human GPAA1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 68 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GPAA1
- ADDITIONAL NAMES: Glycosylphosphatidylinositol anchor attachment 1 protein, GPI anchor attachment protein 1, GAA1 protein homolog, hGAA1, GPAA1, GAA1
- Protein Accession Number: O43292
- NCBI GENE ID NUMBER: 8733
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Posttranslational glycosylphosphatidylinositol (GPI)anchor attachment serves as a general mechanism for linkingproteins to the cell surface membrane. The protein encoded by thisgene presumably functions in GPI anchoring at the GPI transferstep. The mRNA transcript is ubiquitously expressed in both fetaland adult tissues. The anchor attachment protein 1 contains anN-terminal signal sequence, 1 cAMP- and cGMP-dependent proteinkinase phosphorylation site, 1 leucine zipper pattern, 2 potentialN-glycosylation sites, and 8 putative transmembrane domains.
- 1: Jiang, W.W., et al. Mol. Cancer 6, 74 (2007) :
- 2: Olsen, J.V., et al. Cell 127(3):635-648(2006)
- 3: Ho, J.C., et al. Int. J. Cancer 119(6):1330-1337(2006)
- 4: Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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