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GFAP Antibody [SB61b] (Cy3)
CATALOG NUMBER: 99-782- Clonality: Monoclonal
- Tested Applications: ELISA, IHC-Fr, IHC-P
- Host Species: Mouse
- Species Reactivity: Human, Mouse
- Conjugate: Cy3
- Size: 0.5 mg
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: Recombinant human GFAP
- CONJUGATE: Cy3
- TESTED APPLICATIONS: ELISA, IHC-Fr, IHC-P
- APPLICATION NOTE: GFAP Antibody [SB61b] for use in immunohistochemistry / immunocytochemistry and western blotting assays.
- SPECIFICITY: GFAP
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG2b
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: GFAP
- ADDITIONAL NAMES: Glial fibrillary acidic protein, intermediate filament protein
- Protein Accession Number: P14136
- NCBI GENE ID NUMBER: 2670
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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