Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GABRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GABRE.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 58 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GABRE
- ADDITIONAL NAMES: Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilon, GABRE
- Protein Accession Number: P78334
- PROTEIN GI NUMBER: 13124728
- NCBI GENE ID NUMBER: 2564
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The product of this gene belongs to the ligand-gated ionicchannel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid(GABA) A receptor which is a multisubunit chloride channel thatmediates the fastest inhibitory synaptic transmission in thecentral nervous system. This gene encodes an epsilon subunit. It ismapped to chromosome Xq28 in a cluster comprised of genes encodingalpha 3, beta 4 and theta subunits of the same receptor.Alternatively spliced transcript variants have been identified, butonly one is thought to encode a protein.
- 1: Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- 2: Craddock, N., et al. Mol. Psychiatry 15(2):146-153(2010)
- 3: Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
- 4: Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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