FTO Antibody [AG103]
CATALOG NUMBER: 36-093- Clonality: Monoclonal
- Tested Applications: ELISA, IHC, IP, WB
- Host Species: Mouse
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 100 ug
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- IMMUNOGEN: Recombinant human FTO.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC, IP, WB
- APPLICATION NOTE: ELISA: (direct and indirect: 1:2,000-1:5,000). Immunoprecipitation: (5ug/ml per sample in a final reaction volume of 500-1,000ul). Immunohistochemistry: (5-10ug/ml: paraffin sections). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
- SPECIFICITY: Recognizes human FTO.
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG2a, kappa
- PHYSICAL STATE: Liquid
- BUFFER: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
- CONCENTRATION: 1 mg/ml
- STORAGE CONDITIONS: Stable for at least 1 year after receipt when stored at -20°C.
Additional Info
- NCBI OFFICIAL SYMBOL: Fto
- ADDITIONAL NAMES: Fat Mass and Obesity-associated Protein; FATSO
- Protein Accession Number: 166851822
- PROTEIN GI NUMBER: NP_036066.2
- NCBI GENE ID NUMBER: 79068
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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