FPR3 Antibody
CATALOG NUMBER: 56-770- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This FPR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human FPR3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 40 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: FPR3
- ADDITIONAL NAMES: N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2
- Protein Accession Number: P25089
- PROTEIN GI NUMBER: 38258904
- NCBI GENE ID NUMBER: 2359
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
- 1: Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- 2: Kim, S.D., et al. J. Immunol. 183(9):5511-5517(2009)
- 3: Devosse, T., et al. J. Immunol. 182(8):4974-4984(2009)
- 4: Lambert, N.A. Sci Signal(25), RE5 (2008) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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