FOLR3 Antibody
CATALOG NUMBER: 57-159- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This FOLR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human FOLR3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 28 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: FOLR3
- ADDITIONAL NAMES: Folate receptor gamma, FR-gamma, Folate receptor 3, FOLR3
- Protein Accession Number: P41439
- PROTEIN GI NUMBER: 1169723
- NCBI GENE ID NUMBER: 2352
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the folate receptor (FOLR)family, members of which have a high affinity for folic acid andfor several reduced folic acid derivatives, and mediate delivery of5-methyltetrahydrofolate to the interior of cells. This geneincludes two polymorphic variants; the shorter one has two basedeletion in the CDS, resulting in a truncated polypeptide, comparedto the longer one. Both protein products are constitutivelysecreted in hematopoietic tissues and are potential serum markerfor certain hematopoietic malignancies. The longer protein has a71% and 79% sequence homology with the FOLR1 and FOLR2 proteins,respectively.
- 1: O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
- 2: Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- 3: Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
- 4: Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85(3):216-226(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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