Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This FKRP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-265 amino acids from the Central region of human FKRP.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 55 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: FKRP
- ADDITIONAL NAMES: Fukutin-related protein, 2---, FKRP
- Protein Accession Number: Q9H9S5
- PROTEIN GI NUMBER: 46395992
- NCBI GENE ID NUMBER: 79147
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein which is targeted to themedial Golgi apparatus and is necessary for posttranslationalmodification of dystroglycan. Mutations in this gene have beenassociated with congenital muscular dystrophy, mental retardation,and cerebellar cysts. Several alternatively spliced transcriptvariants of this gene have been described, but the full-lengthnature of some of these variants has not been determined. [providedby RefSeq].
- 1: Kawahara, G., et al. Hum. Mol. Genet. 19(4):623-633(2010)
- 2: Crowther-Swanepoel, D., et al. Nat. Genet. 42(2):132-136(2010)
- 3: Lu, P.J., et al. Biochim. Biophys. Acta 1802(2):253-258(2010)
- 4: Hanisch, F., et al. J. Neurol. 257(2):300-301(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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