- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Bovine, Human, Japanese Macaque
- IMMUNOGEN: Microfibrils from the zonular apparatus of bovine eye
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow
- APPLICATION NOTE: Fibrillin Antibody [11C1.3] for use in immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
- SPECIFICITY: Fibrillin
- CLONALITY: Monoclonal
- ISOTYPE: IgG1
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
- CONCENTRATION: 0.2 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
- NCBI OFFICIAL SYMBOL: FBN1
- ADDITIONAL NAMES: FBN1
- Protein Accession Number: Q75N89
- NCBI GENE ID NUMBER: 2200
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear. There is an aberrant expression of fibrillin in Marfan syndrome. The epitope for the monoclonal antibody 11C1.3 has been found to be within exons 18-20 (a.a. 723-909).
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page.
- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 98-519
- Size: 0.2 mg
- List Price: $445.00
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