Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse
- IMMUNOGEN: This FBXO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-251 amino acids from the Central region of human FBXO4.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 44 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: FBXO4
- ADDITIONAL NAMES: F-box only protein 4, FBXO4, FBX4
- Protein Accession Number: Q9UKT5
- PROTEIN GI NUMBER: 60416426
- NCBI GENE ID NUMBER: 26272
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.
- 1: Zeng,Z., et.al., Dev. Cell 18 (2), 214-225 (2010)
- 2: Barbash,O., et.al., Cancer Cell 14 (1), 68-78 (2008)
- 3: Sugiyama,N., et.al., Mol. Cell Proteomics(6), 1103-1109 (2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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