Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Monkey
- IMMUNOGEN: This FBXO15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the N-terminal region of human FBXO15.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 57 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: FBXO15
- ADDITIONAL NAMES: F-box only protein 15, FBXO15, FBX15
- Protein Accession Number: Q8NCQ5
- PROTEIN GI NUMBER: 384872371
- NCBI GENE ID NUMBER: 201456
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Members of the F-box protein family, such as FBXO15, arecharacterized by an approximately 40-amino acid F-box motif. SCFcomplexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM603134), and F-box proteins, act as protein-ubiquitin ligases.F-box proteins interact with SKP1 through the F box, and theyinteract with ubiquitination targets through other proteininteraction domains (Jin et al., 2004 [PubMed 15520277]).[suppliedby OMIM].
- 1: Lamesch, P., et al. Genomics 89(3):307-315(2007)
- 2: Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
- 3: Tokuzawa, Y., et al. Mol. Cell. Biol. 23(8):2699-2708(2003)
- 4: Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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