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- SPECIES: Human, Mouse
- SOURCE SPECIES: HEK293 cells
- RECOMBINANT PROTEIN SEQUENCE: The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
- FUSION TAG: Fc Tag
- APPLICATION NOTE: This recombinant proteins is for research use only.
- BIOLOGICAL ACTIVITY: Blocks the binding of FasL to Fas.
Properties
- PURITY: >95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza). - PHYSICAL STATE: Lyophilized
- BUFFER: Contains PBS. Reconstitute with 50 μl sterile water.
- CONCENTRATION: 1mg/ml after reconstitution.
- STORAGE CONDITIONS: Stable for at least 6 months after receipt when stored at -20°C.
Additional Info
- NCBI OFFICIAL SYMBOL: FAS
- ADDITIONAL NAMES: Tumor Necrosis Factor Receptor Superfamily Member 6, TNFRSF6, Apo-1 Antigen, CD95
- Protein Accession Number: P25445
- PROTEIN GI NUMBER: 4507583
- NCBI GENE ID NUMBER: 355
Background
- FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
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