Ezrin (phospho Tyr146) Antibody
CATALOG NUMBER: 79-961- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Ezrin (phospho Tyr146) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 146 (S-G-Y (p)-L-S) derived from Human Ezrin.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000
- SPECIFICITY: The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 146.
- PREDICTED MOLECULAR WEIGHT: 69 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: EZR
- ADDITIONAL NAMES: Cytovillin, EZRI, p81, VIL2, Villin 2
- Protein Accession Number: NP_001104547.1
- PROTEIN GI NUMBER: 161702986
- NCBI GENE ID NUMBER: 7430
Background
- Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
- 1: Murchie R, et al. (2014)Proc Natl Acad Sci U S A 111, 693-8. Kawahara T, et al. (2013)PLoS One 8, e79654 . Wang Y, Lazo JS (2012)Oncogene 31, 818-27.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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