EPHA3/4/5 (phospho Tyr779/833) Antibody
CATALOG NUMBER: 79-843- Clonality: Polyclonal
- Tested Applications: IHC
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: EPHA3/4/5 (phospho Tyr779/833) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y (p)-T-T)/ (Q-D-V (p)-I-K) derived from Human EPHA3/4/5.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC
- SPECIFICITY: The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.
- PREDICTED MOLECULAR WEIGHT: 110 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: EPHA3, EPHA4
- ADDITIONAL NAMES: EPA3, ETK, HEK, MEK4, REK
- Protein Accession Number: NP_004429.1
- PROTEIN GI NUMBER: 21361241
- NCBI GENE ID NUMBER: 2042;2043
Background
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
- 1: Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615(1992).
- 2: Chiari R., Cancer Res. 60:4855-4863(2000).
- 3: Boyd A.W., J. Biol. Chem. 267:3262-3267(1992).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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