Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse
- IMMUNOGEN: This EIF3K antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the C-terminal region of human EIF3K.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 25 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: EIF3K
- ADDITIONAL NAMES: Eukaryotic translation initiation factor 3 subunit K {ECO:0000255 | HAMAP-Rule:MF_03010}, eIF3k {ECO:0000255 | HAMAP-Rule:MF_03010}, Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000255 | HAMAP-Rule:MF_03010}, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25 {ECO:0000255 | HAMAP-Rule:MF_03010}, eIF-3 p28, EIF3K {ECO:0000255 | HAMAP-Rule:MF_03010}
- Protein Accession Number: Q9UBQ5
- PROTEIN GI NUMBER: 23396628
- NCBI GENE ID NUMBER: 27335
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The 700-kD eukaryotic translation initiation factor-3(eIF3) is the largest eIF and contains at least 12 subunits,including EIF2S12. eIF3 plays an essential role in translation bybinding directly to the 40S ribosomal subunit and promotingformation of the 40S preinitiation complex (Mayeur et al., 2003[PubMed 14519125]).
- 1: Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18139-18144(2008)
- 2: Lin, Y.M., et al. J. Cell. Sci. 121 (PT 14), 2382-2393 (2008) :
- 3: Masutani, M., et al. EMBO J. 26(14):3373-3383(2007)
- 4: Damoc, E., et al. Mol. Cell Proteomics 6(7):1135-1146(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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