DMRT1 Antibody
CATALOG NUMBER: 60-338- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of human DMRT1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 39 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: DMRT1
- ADDITIONAL NAMES: Doublesex- and mab-3-related transcription factor 1, DM domain expressed in testis protein 1, DMRT1, DMT1
- Protein Accession Number: Q9Y5R6
- PROTEIN GI NUMBER: 83305820
- NCBI GENE ID NUMBER: 1761
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is found in a cluster with two other members ofthe gene family, having in common a zinc finger-like DNA-bindingmotif (DM domain). The DM domain is an ancient, conserved componentof the vertebrate sex-determining pathway that is also a keyregulator of male development in flies and nematodes. This geneexhibits a gonad-specific and sexually dimorphic expressionpattern. Defective testicular development and XY feminization occurwhen this gene is hemizygous.
- 1: Kang, J.U., et al. Int. J. Oncol. 37(2):327-335(2010)
- 2: Turnbull, C., et al. Nat. Genet. 42(7):604-607(2010)
- 3: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 4: Krentz, A.D., et al. Proc. Natl. Acad. Sci. U.S.A. 106(52):22323-22328(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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