Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This DFNB31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human DFNB31.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 97 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: DFNB31
- ADDITIONAL NAMES: Whirlin, Autosomal recessive deafness type 31 protein, DFNB31, KIAA1526, WHRN
- Protein Accession Number: Q9P202
- PROTEIN GI NUMBER: 296453079
- NCBI GENE ID NUMBER: 25861
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is thought to function in the organization andstabilization of sterocilia elongation and actin cystoskeletalassembly, based on studies of the related mouse gene. Mutations inthis gene have been associated with autosomal recessivenon-syndromic deafness and Usher Syndrome. Alternative splicing ofthis gene results in multiple transcript variants encodingdifferent isoforms.
- 1: Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :
- 2: Secolin, R., et al. Psychiatr. Genet. 20(3):126-129(2010)
- 3: Aller, E., et al. Mol. Vis. 16, 495-500 (2010) :
- 4: Toiyama, Y., et al. Int. J. Oncol. 35(4):709-715(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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