DDX21 Antibody
CATALOG NUMBER: 59-054- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:2000
- PREDICTED MOLECULAR WEIGHT: 87 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: DDX21
- ADDITIONAL NAMES: Nucleolar RNA helicase 2, DEAD box protein 21, Gu-alpha, Nucleolar RNA helicase Gu, Nucleolar RNA helicase II, RH II/Gu, DDX21
- Protein Accession Number: Q9NR30
- PROTEIN GI NUMBER: 76803555
- NCBI GENE ID NUMBER: 9188
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- DEAD box proteins, characterized by the conserved motifAsp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They areimplicated in a number of cellular processes involving alterationof RNA secondary structure such as translation initiation, nuclearand mitochondrial splicing, and ribosome and spliceosome assembly.Based on their distribution patterns, some members of this familyare believed to be involved in embryogenesis, spermatogenesis, andcellular growth and division. This gene encodes a DEAD box protein,which is an antigen recognized by autoimmune antibodies from apatient with watermelon stomach disease. This protein unwindsdouble-stranded RNA, folds single-stranded RNA, and may playimportant roles in ribosomal RNA biogenesis, RNA editing, RNAtransport, and general transcription.
- 1: Holmstrom, T.H., et al. J. Biol. Chem. 283(11):7046-7053(2008)
- 2: Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- 3: Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- 4: Olsen, J.V., et al. Cell 127(3):635-648(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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