DAO Antibody
CATALOG NUMBER: 57-366- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 39 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: DAO
- ADDITIONAL NAMES: D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
- Protein Accession Number: P14920
- PROTEIN GI NUMBER: 25453448
- NCBI GENE ID NUMBER: 1610
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes the peroxisomal enzyme D-amino acidoxidase. The enzyme is a flavoprotein which uses flavin adeninedinucleotide (FAD) as its prosthetic group. Its substrates includea wide variety of D-amino acids, but it is inactive on thenaturally occurring L-amino acids. Its biological function is notknown; it may act as a detoxifying agent which removes D-aminoacids that accumulate during aging. In mice, it degrades D-serine,a co-agonist of the NMDA receptor. This gene may play a role in thepathophysiology of schizophrenia.
- 1: Kim, B., et al. Psychiatry Res 179(2):121-125(2010)
- 2: Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)
- 3: Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- 4: Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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