DACH2 Antibody
CATALOG NUMBER: 56-944- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 65 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: DACH2
- ADDITIONAL NAMES: Dachshund homolog 2, Dach2, DACH2
- Protein Accession Number: Q96NX9
- PROTEIN GI NUMBER: 44887818
- NCBI GENE ID NUMBER: 117154
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is one of two genes which encode a proteinsimilar to the Drosophila protein dachshund, a transcription factorinvolved in cell fate determination in the eye, limb and genitaldisc of the fly. The encoded protein contains two characteristicdachshund domains: an N-terminal domain responsible for DNA bindingand a C-terminal domain responsible for protein-proteininteractions. This gene is located on the X chromosome and issubject to inactivation by DNA methylation. The encoded protein maybe involved in regulation of organogenesis and myogenesis, and mayplay a role in premature ovarian failure. Multiple transcriptvariants encoding different isoforms have been found for this gene.
- 1: Bailey, S.D., et al. Diabetes Care (2010) In press :
- 2: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- 3: Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
- 4: Poulin, F., et al. Genomics 85(6):774-781(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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