CYBB Antibody
CATALOG NUMBER: 42-007- Clonality: Polyclonal
- Tested Applications: E, IHC
- Host Species: Goat
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Goat
- SPECIES REACTIVITY: Human
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Dog
- IMMUNOGEN: The immunogen for this antibody is: C-SYLNFARKRIKNP
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, IHC
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:64000.Immunohistochemistry:In paraffin embedded Human Placenta shows staining of syncytiotrophoblasts. Recommended concentration, 1-2ug/ml.
- POSITIVE CONTROL 1: Cat. No. 1371 - Human peripheral blood leukocyte (PBL) Lysate
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: CYBB
- ADDITIONAL NAMES: CYBB, cytochrome b-245, beta polypeptide (chronic granulomatous disease), CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, cytochrome b-245, beta polypeptide
- Protein Accession Number: NP_000388.2
- PROTEIN GI NUMBER: 6996021
- NCBI GENE ID NUMBER: 1536
Background
- 1: Zhu C, Lindsey S, Konieczna I, Eklund EA. Constitutive activation of SHP2 protein tyrosine phosphatase inhibitsICSBP-induced transcription of the gene encoding gp91PHOX during myeloiddifferentiation. J Leukoc Biol. 2008 Mar;83(3):680-91.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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