CSTA Antibody
CATALOG NUMBER: 57-666- Clonality: Polyclonal
- Tested Applications: IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This CSTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human CSTA.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 11 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CSTA
- ADDITIONAL NAMES: Cystatin-A, Cystatin-AS, Stefin-A, Cystatin-A, N-terminally processed, CSTA, STF1, STFA
- Protein Accession Number: P01040
- PROTEIN GI NUMBER: 118177
- NCBI GENE ID NUMBER: 1475
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins, and kininogens. This gene encodes astefin that functions as a cysteine protease inhibitor, formingtight complexes with papain and the cathepsins B, H, and L. Theprotein is one of the precursor proteins of cornified cell envelopein keratinocytes and plays a role in epidermal development andmaintenance. Stefins have been proposed as prognostic anddiagnostic tools for cancer.
- 1: O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19(21):4296-4303(2010)
- 2: Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)
- 3: Takai, T., et al. J. Immunol. 183(12):7958-7965(2009)
- 4: Vasilopoulos, Y., et al. Eur. J. Hum. Genet. 16(8):1002-1009(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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