CRYM Antibody
CATALOG NUMBER: 60-710- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 34 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CRYM
- ADDITIONAL NAMES: Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
- Protein Accession Number: Q14894
- PROTEIN GI NUMBER: 2498259
- NCBI GENE ID NUMBER: 1428
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Crystallins are separated into two classes: taxon-specificand ubiquitous. The former class is also calledphylogenetically-restricted crystallins. The latter classconstitutes the major proteins of vertebrate eye lens and maintainsthe transparency and refractive index of the lens. This geneencodes a taxon-specific crystallin protein that binds NADPH andhas sequence similarity to bacterial ornithine cyclodeaminases. Theencoded protein does not perform a structural role in lens tissue,and instead it binds thyroid hormone for possible regulatory ordevelopmental roles. Mutations in this gene have been associatedwith autosomal dominant non-syndromic deafness. Multiplealternatively spliced transcript variants have been found for thisgene.
- 1: Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
- 2: Al-Kafaji, G., et al. Biochem. Biophys. Res. Commun. 391(4):1585-1591(2010)
- 3: Malinowska, K., et al. Prostate 69(10):1109-1118(2009)
- 4: Martins-de-Souza, D., et al.Psychiatr Res 43(11):978-986(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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