CPN1 Antibody
CATALOG NUMBER: 56-714- Clonality: Polyclonal
- Tested Applications: Flow, IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human CPN1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 52 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CPN1
- ADDITIONAL NAMES: Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, Serum carboxypeptidase N, SCPN, CPN1, ACBP
- Protein Accession Number: P15169
- PROTEIN GI NUMBER: 115896
- NCBI GENE ID NUMBER: 1369
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Carboxypeptidase N is a plasma metallo-protease thatcleaves basic amino acids from the C terminal of peptides andproteins. The enzyme is important in the regulation of peptideslike kinins and anaphylatoxins, and has also been known askininase-1 and anaphylatoxin inactivator. This enzyme is a tetramercomprised of two identical regulatory subunits and two identicalcatalytic subunits; this gene encodes the catalytic subunit.Mutations in this gene can be associated with angioedema or chronicurticaria resulting from carboxypeptidase N deficiency. [providedby RefSeq].
- 1: Speliotes, E.K., et al. Hepatology 52(3):904-912(2010)
- 2: Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
- 3: Du, X.Y., et al. J. Biol. Chem. 284(2):751-758(2009)
- 4: Yuan, X., et al. Am. J. Hum. Genet. 83(4):520-528(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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