Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 209-458 of human CPN1 (NP_001299.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: MCF7
- POSITIVE CONTROL 2: Raji
- POSITIVE CONTROL 3: Mouse liver
- POSITIVE CONTROL 4: Mouse pancreas
- POSITIVE CONTROL 5: Rat brain
- PREDICTED MOLECULAR WEIGHT: Observed: 52kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: CPN1
- ADDITIONAL NAMES: CPN1, CPN, FLJ40792, SCPN
- NCBI GENE ID NUMBER: 1369
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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