Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
- IMMUNOGEN: This COPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the Central region of human COPB1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 107 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: COPB1
- ADDITIONAL NAMES: Coatomer subunit beta, Beta-coat protein, Beta-COP, COPB1, COPB
- Protein Accession Number: P53618
- PROTEIN GI NUMBER: 116241311
- NCBI GENE ID NUMBER: 1315
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein subunit of the coatomercomplex associated with non-clathrin coated vesicles. The coatomercomplex, also known as the coat protein complex 1, forms in thecytoplasm and is recruited to the Golgi by activated guanosinetriphosphatases. Once at the Golgi membrane, the coatomer complexmay assist in the movement of protein and lipid components back tothe endoplasmic reticulum. Alternatively spliced transcriptvariants have been described.
- 1: Burman, J.L., et al. J. Biol. Chem. 283(33):22774-22786(2008)
- 2: Lippincott-Schwartz, J., et al. Trends Cell Biol. 16 (10), E1-E4 (2006) :
- 3: Huang, L., et al. Mol. Biol. Rep. 29(3):317-323(2002)
- 4: Paulsson, K.M., et al. J. Biol. Chem. 277(21):18266-18271(2002)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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