COL6A2 Antibody
CATALOG NUMBER: 58-453- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 109 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: COL6A2
- ADDITIONAL NAMES: Collagen alpha-2(VI) chain, COL6A2
- Protein Accession Number: P12110
- PROTEIN GI NUMBER: 125987812
- NCBI GENE ID NUMBER: 1292
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- COL6A2 is one of the three alpha chains of type VIcollagen, a beaded filament collagen found in most connectivetissues. The product of this gene contains several domains similarto von Willebrand Factor type A domains. These domains have beenshown to bind extracellular matrix proteins, an interaction thatexplains the importance of this collagen in organizing matrixcomponents. Mutations in this gene are associated with Bethlemmyopathy and Ullrich scleroatonic muscular dystrophy. Threetranscript variants have been identified for this gene. [providedby RefSeq].
- 1: Zhang, R.Z., et al. J. Biol. Chem. 285(13):10005-10015(2010)
- 2: Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :
- 3: Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
- 4: Freise, C., et al. Matrix Biol. 28(8):480-489(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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