CLC Antibody
CATALOG NUMBER: 58-277- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the C-terminal region of human CLC.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 16 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CLC
- ADDITIONAL NAMES: Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A
- Protein Accession Number: Q05315
- PROTEIN GI NUMBER: 317373429
- NCBI GENE ID NUMBER: 1178
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Lysophospholipases are enzymes that act on biologicalmembranes to regulate the multifunctional lysophospholipids. Theprotein encoded by this gene is a lysophospholipase expressed ineosinophils and basophils. It hydrolyzes lysophosphatidylcholine toglycerophosphocholine and a free fatty acid. This protein maypossess carbohydrate or IgE-binding activities. It is bothstructurally and functionally related to the galectin family ofbeta-galactoside binding proteins. It may be associated withinflammation and some myeloid leukemias.
- 1: Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- 2: Bryborn, M., et al. Allergy 65(2):220-228(2010)
- 3: De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :
- 4: Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106(24):9731-9736(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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