Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This CEBPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-232 amino acids from the C-terminal region of human CEBPE.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 31 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: CEBPE
- ADDITIONAL NAMES: CCAAT/enhancer-binding protein epsilon, C/EBP epsilon, CEBPE
- Protein Accession Number: Q15744
- PROTEIN GI NUMBER: 62512175
- NCBI GENE ID NUMBER: 1053
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is a bZIP transcriptionfactor which can bind as a homodimer to certain DNA regulatoryregions. It can also form heterodimers with the related proteinCEBP-delta. The encoded protein may be essential for terminaldifferentiation and functional maturation of committed granulocyteprogenitor cells. Mutations in this gene have been associated withSpecific Granule Deficiency, a rare congenital disorder. Multiplevariants of this gene have been described, but the full-lengthnature of only one has been determined.
- 1: Prasad, R.B., et al. Blood (2009) In press :
- 2: Papaemmanuil, E., et al. Nat. Genet. 41(9):1006-1010(2009)
- 3: Bedi, R., et al. Blood 113(2):317-327(2009)
- 4: Cloutier, A., et al. J. Immunol. 182(1):563-571(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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