Specifications
- HOST SPECIES: Goat
- SPECIES REACTIVITY: Human
- IMMUNOGEN: The immunogen for this antibody is: C-ILRKKGRLPGEFSE
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, WB
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 17kDa band observed in lysates of cell line HeLa (calculated MW of 12.1kDa according to NP_478104.1). Recommended concentration: 1-3ug/ml.
- SPECIFICITY: This antibody is expected to recognize the pancreas isoform (NP_478104.1) only.
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: CDKN2A
- ADDITIONAL NAMES: CDKN2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , HGNC:1787, ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, TP16, p14, p14ARF, p16, p16INK4, p16INK4a, p19 , CDK4 inhibitor p16-INK4, cell cycle negative regulator beta, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A, p14ARF, cyclin-dependent kinase inhibitor p12, p16INK4a alternatively spliced form, cyclin-dependent kinase inhibitor p16, multiple tumor suppressor 1
- Protein Accession Number: NP_478104.1
- PROTEIN GI NUMBER: 17738298
- NCBI GENE ID NUMBER: 1029
Background
- 1: Normand G, Hemmati PG, Verdoodt B, von Haefen C, Wendt J, Guner D, May E, Dorken B, Daniel PT. p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity. J Biol Chem. 2005 Feb 25;280(8):7118-30. Epub 2004 Dec 6.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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