Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: A synthetic peptide corresponding to a sequence within amino acids 208-258 of human CDK1 (NP_001777.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, IP, WB
- APPLICATION NOTE: WB: 1:200 - 1:1000
IHC: 1:50 - 1:100
IP: 1:50 - 1:100 - POSITIVE CONTROL 1: HeLa
- POSITIVE CONTROL 2: Jurkat
- POSITIVE CONTROL 3: Mouse thymus
- PREDICTED MOLECULAR WEIGHT: Observed: 35kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: CDK1
- ADDITIONAL NAMES: CDC2, CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
- NCBI GENE ID NUMBER: 983
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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