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CD86 Antibody [2C5B4]
CATALOG NUMBER: 13-807- Clonality: Monoclonal
- Tested Applications: IF, IHC, IP, WB
- Host Species: Rabbit
- Species Reactivity: Human, Rat
- Conjugate: Unconjugated
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Rat
- IMMUNOGEN: Recombinant protein of human CD86
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:100 - POSITIVE CONTROL 1: Raji
- POSITIVE CONTROL 2: Jurkat
- PREDICTED MOLECULAR WEIGHT: Observed: 70kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Monoclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: CD86
- ADDITIONAL NAMES: CD86 Antibody: CD86 molecule, B70, B7-2, B7.2, LAB72, CD28LG2
- NCBI GENE ID NUMBER: 942
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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