CD86 Antibody [24F] (FITC)
CATALOG NUMBER: 76-606- Clonality: Monoclonal
- Tested Applications: Flow
- Host Species: Mouse
- Species Reactivity: Rat
- Conjugate: FITC
- Size: 0.1 mg
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Rat
- CONJUGATE: FITC
- TESTED APPLICATIONS: Flow
- SPECIFICITY: The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- CLONALITY: Monoclonal
- ISOTYPE: Mouse IgG1, kappa
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: Cd86
- ADDITIONAL NAMES: B7-2, Cd86
- NCBI GENE ID NUMBER: 56822
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
- 1: Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997). Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology,9(7), 993-1000.
- 2: Damoiseaux, J. G., Yagita, H., Okumura, K., van Breda Vriesman, P. J. (1998). Costimulatory molecules CD80 and CD86 in the rat
- 3: tissue distribution and expression by antigen-presenting cells.Journal of leukocyte biology,64(6), 803-809.
- 4: BLUESTONE, J. (1995). New perspectives of CD28-B7-mediated T cell costimulation.Immunity,2, 555-559.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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