CD81 Antibody [2F7] (FITC)
CATALOG NUMBER: 98-991- Clonality: Monoclonal
- Tested Applications: Flow, IHC-Fr, IP, Separation, WB
- Host Species: Hamster
- Species Reactivity: Mouse
- Conjugate: FITC
- Size: 0.5 mg
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- HOST SPECIES: Hamster
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: Mouse epithelial cell line PAM212
- CONJUGATE: FITC
- TESTED APPLICATIONS: Flow, IHC-Fr, IP, Separation, WB
- APPLICATION NOTE: CD81 Antibody [2F7] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
- SPECIFICITY: CD81
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: Cd81
- ADDITIONAL NAMES: TAPA-1
- Protein Accession Number: P35762
- NCBI GENE ID NUMBER: 12520
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alphabeta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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