Specifications
- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: DBA/2 mouse spleen cells
- CONJUGATE: FITC
- TESTED APPLICATIONS: Blocking, Flow, ICC, IHC-Fr, IP, WB
- APPLICATION NOTE: CD72.1 Antibody [10.1.D2] for use in flow cytometry assays.
- SPECIFICITY: CD72.1
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG2b
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: Cd72
- ADDITIONAL NAMES: Lyb-2.1, CD72a, Lyb-2a
- Protein Accession Number: P21855
- NCBI GENE ID NUMBER: 12517
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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