Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: CD44 (phospho Ser706) antibody was raised against a peptide sequence around phosphorylation site of serine 706 (S-K-S (p)-Q-E) derived from Human CD44.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000
- SPECIFICITY: The antibody detects endogenous level of CD44 only when phosphorylated at serine 706.
- PREDICTED MOLECULAR WEIGHT: 81, 90, kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: CD44
- ADDITIONAL NAMES: CD44 antigen precursor, ECMR-III, Epican, Hermes antigen, PGP-1
- Protein Accession Number: NP_000601.3
- PROTEIN GI NUMBER: 48255935
- NCBI GENE ID NUMBER: 960
Background
- Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
- 1: Ildefonso CJ, et al. (2012)J Biol Chem 287, 32697-707. Pivetta E, et al. (2011)J Cell Physiol 226, 769-79. Wang YT, et al. (2010)J Proteome Res 9, 5582-97.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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