- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human, Ma's Night Monkey
- IMMUNOGEN: Purified human T cells
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC-Fr
- APPLICATION NOTE: CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.
- SPECIFICITY: CD44
- CLONALITY: Monoclonal
- ISOTYPE: IgG2a
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Store vial at -20°C
- NCBI OFFICIAL SYMBOL: CD44
- ADDITIONAL NAMES: Pgp-1, H-CAM, ECMR-III, HUTCH-1
- Protein Accession Number: P16070
- NCBI GENE ID NUMBER: 960
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 99-380
- Size: 0.5 mg
- List Price: $535.00
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