CD30 Antibody [mCD30.1]
CATALOG NUMBER: 76-017- Clonality: Monoclonal
- Tested Applications: Flow, Functional Assays
- Host Species: Hamster
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 0.05 mg
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- HOST SPECIES: Hamster
- SPECIES REACTIVITY: Mouse
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, Functional Assays
- SPECIFICITY: The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily.
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
- CLONALITY: Monoclonal
- ISOTYPE: Armenian Hamster IgG
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C . Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: Tnfrsf8
- ADDITIONAL NAMES: Ki, Cd30, Ki-1, D1S166E, Tnfrsf8
- NCBI GENE ID NUMBER: 21941
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
- 1: Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2.Diabetes,49(9), 1612-1616.
- 2: Falini, B., Pileri, S., Pizzolo, G., D, H., Flenghi, L., Stirpe, F., ... Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.BLOOD-NEW YORK-,85, 1-1.
- 3: Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., Miller, J. F. (1999). CD 30 prevents Tcell responses to nonlymphoid tissues.Immunological reviews,169(1), 23-29.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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