Specifications
- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- IMMUNOGEN: Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes
- CONJUGATE: APC-Cy7
- TESTED APPLICATIONS: Flow, IHC-Fr
- APPLICATION NOTE: CD3 Antibody [UCHT1] for use in flow cytometry assays.
- SPECIFICITY: CD3
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG1
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3 and a stabilizing agent
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: CD3E
- ADDITIONAL NAMES: CD3epsilon, T3E, TCRE, Leu-4, T3
- Protein Accession Number: P07766
- NCBI GENE ID NUMBER: 916
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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