Specifications
- HOST SPECIES: Hamster
- SPECIES REACTIVITY: Human
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, Functional Assays
- SPECIFICITY: The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. .
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
- CLONALITY: Monoclonal
- ISOTYPE: Armenian Hamster IgG
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C . Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: CD27
- ADDITIONAL NAMES: T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27
- NCBI GENE ID NUMBER: 939
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.7F9 antibody is cross-reactive human, mouse, and rat CD27.
- 1: Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005). Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175(12), 8415-8423.
- 2: Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- 3: Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985). Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66(1), 64-68.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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