CD20 Antibody [2H7]
CATALOG NUMBER: 76-004- Clonality: Monoclonal
- Tested Applications: Flow, IHC
- Host Species: Mouse
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC
- SPECIFICITY: The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule.
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography.
- CLONALITY: Monoclonal
- ISOTYPE: Mouse IgG2b, kappa
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C . Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: MS4A1
- ADDITIONAL NAMES: B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1
- NCBI GENE ID NUMBER: 931
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
- 1: Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- 2: Polyak, M. J., Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes
- 3: Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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