Specifications
- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- CONJUGATE: FITC
- TESTED APPLICATIONS: Flow
- SPECIFICITY: The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein.
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- CLONALITY: Monoclonal
- ISOTYPE: Mouse IgG1, kappa
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: CD1A
- ADDITIONAL NAMES: R4, T6, CD1, FCB6, HTA1, CD1A
- NCBI GENE ID NUMBER: 909
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein. It is expressed on dendritic cells, Langerhans cells, and cortical thymocytes. CD1a plays a role in antigen presentation and ,like MHC Class I, it non-covalently associates with Beta2-microglobulin.
- 1: Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
- 2: Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- 3: Hanau, D., Schmitt, D. A., Bieber, T., Schmitt, D., Cazenave, J. P. (1990). Possible mechanism of action of CD1a antigens.Journal of investigative dermatology,95(5), 503-505.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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