CD158e1 Antibody [DX9] (PE)
CATALOG NUMBER: 99-609- Clonality: Monoclonal
- Tested Applications: Flow
- Host Species: Mouse
- Species Reactivity: Baboon, Human
- Conjugate: PE
- Size: 100 tests
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Baboon, Human
- IMMUNOGEN: Human NK clone VL186-1 (CD3-, CD16+, CD56+)
- CONJUGATE: PE
- TESTED APPLICATIONS: Flow
- APPLICATION NOTE: CD158e1 Antibody [DX9] for use in flow cytometry assays.
- SPECIFICITY: CD158e1
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG1
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3 and a stabilizing agent
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: KIR3DL1
- ADDITIONAL NAMES: NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3
- Protein Accession Number: P43629
- NCBI GENE ID NUMBER: 3811
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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