Specifications
- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, Functional Assays
- SPECIFICITY: The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS).
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
- CLONALITY: Monoclonal
- ISOTYPE: Mouse IgG1, kappa
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C . Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: CD14
- ADDITIONAL NAMES: CD14, CD14
- NCBI GENE ID NUMBER: 929
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS). It is expressed on some dendritic cells, monocytes, and neutrophils. CD14 is involved in the body’s innate immune response and cytokine expression in monocytes and neutrophils.
- 1: Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
- 2: Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
- 3: Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells.Nature,392(6675), 505-509.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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