Specifications
- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Cynomolgus Monkey, Human, Rhesus Monkey
- IMMUNOGEN: Rheumatoid synovial cells and human monocytes
- CONJUGATE: PE
- TESTED APPLICATIONS: Flow
- APPLICATION NOTE: CD11c Antibody [3.9] for use in flow cytometry assays.
- SPECIFICITY: CD11c
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG1
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3 and a stabilizing agent
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: ITGAX
- ADDITIONAL NAMES: Integrin alphaX, Axb2, CR4, p150,95
- Protein Accession Number: P20702
- NCBI GENE ID NUMBER: 3687
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- CD11c is a 150 kDa adhesion glycoprotein that associates with beta2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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